ZFIN is now using GRCz12tu for Genomic Data
Gene
spo11
- ID
- ZDB-GENE-040426-1900
- Name
- SPO11 initiator of meiotic double stranded breaks
- Symbol
- spo11 Nomenclature History
- Previous Names
-
- zgc:77876 (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA binding activity. Acts upstream of or within chromosome organization involved in meiotic cell cycle. Predicted to be located in chromosome. Predicted to be active in nuclear chromosome. Is expressed in testis. Orthologous to human SPO11 (SPO11 initiator of meiotic double strand breaks).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77876 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR013049 | Spo11/DNA topoisomerase VI, subunit A, N-terminal |
| Domain | IPR034136 | Topoisomerase 6 subunit A/Spo11, TOPRIM domain |
| Family | IPR002815 | Spo11/DNA topoisomerase VI subunit A |
| Family | IPR013048 | Meiotic recombination, Spo11 |
| Homologous_superfamily | IPR036078 | Spo11/DNA topoisomerase VI subunit A superfamily |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Meiotic recombination, Spo11 | Spo11/DNA topoisomerase VI subunit A | Spo11/DNA topoisomerase VI, subunit A, N-terminal | Spo11/DNA topoisomerase VI subunit A superfamily | Topoisomerase 6 subunit A/Spo11, TOPRIM domain | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6P0S6 | InterPro | 383 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers