Gene

u2af2b

ID

ZDB-GENE-040426-1881

Name

U2 small nuclear RNA auxiliary factor 2b

Symbol

u2af2b Nomenclature History

Previous Names

wu:fb73g02
zgc:77804

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have poly-pyrimidine tract binding activity and pre-mRNA 3'-splice site binding activity. Predicted to be involved in RNA splicing and mRNA processing. Predicted to localize to nucleus. Orthologous to human U2AF2 (U2 small nuclear RNA auxiliary factor 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:77804 (1 image)
IMAGE:7162798 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With u2af2b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
developmental delay, dysmorphic facies, and brain anomalies	Alliance	Developmental delay, dysmorphic facies, and brain anomalies	620535

Associated With u2af2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Family	IPR006529	U2 snRNP auxilliary factor, large subunit, splicing factor
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Nucleotide-binding alpha-beta plait domain superfamily	RNA-binding domain superfamily	RNA recognition motif domain	U2 snRNP auxilliary factor, large subunit, splicing factor
UniProtKB:A0A0R4IMP0 InterPro	480
UniProtKB:Q6P022 InterPro	475
UniProtKB:A0A8M3AVC4 InterPro	463
UniProtKB:A0A8M3AK10 InterPro	456
UniProtKB:A0A8M3ASD1 InterPro	461
UniProtKB:A0A8M3AK05 InterPro	479
UniProtKB:A0A8M3AKT5 InterPro	468
UniProtKB:A0A8M3B3C5 InterPro	473

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	u2af2b-201 (1) Ensembl	Havana	2665 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	u2af2b-203 (1) Ensembl	Havana	858 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	u2af2b-204 (1) Ensembl	Havana	836 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	u2af2b-205 (1) Ensembl	Havana	735 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	u2af2b-206 (1) Ensembl	Havana	890 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	u2af2b-207 (1) Ensembl	Havana	824 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	u2af2b-005 (1) Ensembl	Havana	789 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations