Gene
scp2a
- ID
- ZDB-GENE-040426-1846
- Name
- sterol carrier protein 2a
- Symbol
- scp2a Nomenclature History
- Previous Names
-
- scp2
- zgc:77634
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable acetyl-CoA C-acyltransferase activity; acetyl-CoA C-myristoyltransferase activity; and lipid binding activity. Predicted to act upstream of or within lipid metabolic process and lipid transport. Predicted to be located in mitochondrion. Predicted to be active in peroxisome. Is expressed in intestinal bulb; lens; liver; and solid lens vesicle. Orthologous to human SCP2 (sterol carrier protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77634 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
?Leukoencephalopathy with dystonia and motor neuropathy | 613724 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR020615 | Thiolase, acyl-enzyme intermediate active site |
Conserved_site | IPR020613 | Thiolase, conserved site |
Domain | IPR003033 | SCP2 sterol-binding domain |
Domain | IPR020616 | Thiolase, N-terminal |
Domain | IPR055140 | Thiolase, C-terminal domain 2 |
Homologous_superfamily | IPR016039 | Thiolase-like |
Homologous_superfamily | IPR036527 | SCP2 sterol-binding domain superfamily |
Domain Details Per Protein
Protein | Additional Resources | Length | SCP2 sterol-binding domain | SCP2 sterol-binding domain superfamily | Thiolase, acyl-enzyme intermediate active site | Thiolase, conserved site | Thiolase, C-terminal domain 2 | Thiolase-like | Thiolase, N-terminal |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:Q6P4V5 | InterPro PDB | 538 | |||||||
UniProtKB:A0A8M2BA96 | InterPro | 332 |
Interactions and Pathways
No data available
Plasmids
No data available