Gene
tfdp1b
- ID
- ZDB-GENE-040426-1746
- Name
- transcription factor Dp-1, b
- Symbol
- tfdp1b Nomenclature History
- Previous Names
-
- tfdp1 (1)
- hm:zeh1183
- zeh1183
- zgc:73281
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to contribute to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of cell cycle. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in adaxial cell; alar plate midbrain region; nervous system; and optic vesicle. Human ortholog(s) of this gene implicated in mismatch repair cancer syndrome. Orthologous to human TFDP1 (transcription factor Dp-1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73281 (7 images)
- IMAGE:6906520 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
| Domain | IPR014889 | Transcription factor DP, C-terminal |
| Family | IPR015648 | Transcription factor DP |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
| Homologous_superfamily | IPR037241 | E2F-DP heterodimerization region |
| Homologous_superfamily | IPR038168 | Transcription factor DP, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | E2F/DP family, winged-helix DNA-binding domain | E2F-DP heterodimerization region | Transcription factor DP | Transcription factor DP, C-terminal | Transcription factor DP, C-terminal domain superfamily | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3B341 | InterPro | 381 | |||||||
| UniProtKB:F1R508 | InterPro | 385 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tfdp1b-201
(1)
|
Ensembl | 1,682 nt | ||
| mRNA |
tfdp1b-202
(1)
|
Ensembl | 3,555 nt |
Interactions and Pathways
No data available
Plasmids
No data available