Gene

prmt7

ID
ZDB-GENE-040426-1560
Name
protein arginine methyltransferase 7
Symbol
prmt7 Nomenclature History
Previous Names
  • zgc:66172
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to enable histone H4R3 methyltransferase activity and protein-arginine omega-N symmetric methyltransferase activity. Acts upstream of with a negative effect on defense response to virus. Acts upstream of or within with a positive effect on cytoskeleton organization. Acts upstream of or within epiboly involved in gastrulation with mouth forming second. Predicted to be located in cytosol and nucleus. Is expressed in adaxial cell; brain; eye; otic vesicle; and somite. Orthologous to human PRMT7 (protein arginine methyltransferase 7).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
ihbp4Allele with one deletionUnknownUnknownCRISPR
ihbp7Allele with one delinsUnknownUnknownCRISPR
sa552Allele with one point mutationUnknownSplice SiteENU
sa38029Allele with one point mutationUnknownSplice SiteENU
sa44256Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-prmt7 (2)
MO1-prmt7N/A (2)
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Human Disease
Associated With prmt7 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Short stature, brachydactyly, intellectual developmental disability, and seizures 617157
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Associated With prmt7 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR055135 Protein arginine N-methyltransferase domain
Family IPR014644 Protein arginine N-methyltransferase PRMT7
Family IPR025799 Protein arginine N-methyltransferase
Homologous_superfamily IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
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Domain Details Per Protein
Protein Additional Resources Length Protein arginine N-methyltransferase Protein arginine N-methyltransferase domain Protein arginine N-methyltransferase PRMT7 S-adenosyl-L-methionine-dependent methyltransferase superfamily
UniProtKB:A2AV36 InterPro 683
UniProtKB:A0A8M6YVX1 InterPro 550
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 25
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA prmt7-201 (1) Ensembl 2,526 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-51L3ZFIN Curated Data
EncodescDNAMGC:66172ZFIN Curated Data
EncodescDNAMGC:191898ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanPRMT716
Conserved genome location (synteny) (1)
Amino acid sequence comparison (2)
MousePrmt78
Amino acid sequence comparison (2)
Conserved genome location (synteny) (1)
Citations
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