Gene
prmt7
- ID
- ZDB-GENE-040426-1560
- Name
- protein arginine methyltransferase 7
- Symbol
- prmt7 Nomenclature History
- Previous Names
-
- zgc:66172
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable histone H4R3 methyltransferase activity and protein-arginine omega-N symmetric methyltransferase activity. Acts upstream of with a negative effect on defense response to virus. Acts upstream of or within with a positive effect on cytoskeleton organization. Acts upstream of or within epiboly involved in gastrulation with mouth forming second. Predicted to be located in cytosol and nucleus. Is expressed in adaxial cell; brain; eye; otic vesicle; and somite. Orthologous to human PRMT7 (protein arginine methyltransferase 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66172 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Short stature, brachydactyly, intellectual developmental disability, and seizures | 617157 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Protein arginine N-methyltransferase | Protein arginine N-methyltransferase domain | Protein arginine N-methyltransferase PRMT7 | S-adenosyl-L-methionine-dependent methyltransferase superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:A2AV36 | InterPro | 683 | ||||
| UniProtKB:A0A8M6YVX1 | InterPro | 550 |
Interactions and Pathways
No data available
Plasmids
No data available