Gene
cpeb4a
- ID
- ZDB-GENE-040426-1557
- Name
- cytoplasmic polyadenylation element binding protein 4a
- Symbol
- cpeb4a Nomenclature History
- Previous Names
-
- cpeb4
- zgc:66166 (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable several functions, including mRNA 3'-UTR binding activity; mRNA regulatory element binding translation repressor activity; and translation factor activity, RNA binding. Predicted to be involved in several processes, including cellular response to glucose starvation; negative regulation of cytoplasmic translation; and response to ischemia. Predicted to act upstream of or within regulation of translation. Predicted to be located in dendrite; endoplasmic reticulum; and postsynaptic density. Predicted to be active in several cellular components, including neuron projection; nucleus; and synapse. Is expressed in cranial ganglion; neurons; olfactory placode; peripheral olfactory organ; and yolk syncytial layer. Orthologous to human CPEB4 (cytoplasmic polyadenylation element binding protein 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66166 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000504 | RNA recognition motif domain |
Domain | IPR032296 | Cytoplasmic polyadenylation element-binding protein, ZZ domain |
Family | IPR034819 | Cytoplasmic polyadenylation element-binding protein |
Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
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Domain Details Per Protein
Protein | Additional Resources | Length | CEBP, ZZ domain superfamily | Cytoplasmic polyadenylation element-binding protein | Cytoplasmic polyadenylation element-binding protein, ZZ domain | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain |
---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M6Z9E0 | InterPro | 519 | ||||||
UniProtKB:F1QCY1 | InterPro | 703 | ||||||
UniProtKB:A0A8M6Z2L6 | InterPro | 511 | ||||||
UniProtKB:A0A8M3AHT9 | InterPro | 711 | ||||||
UniProtKB:B2GRL1 | InterPro | 635 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
cpeb4a-201
(1)
|
Ensembl | 4,983 nt | ||
mRNA |
cpeb4a-202
(1)
|
Ensembl | 5,031 nt | ||
mRNA |
cpeb4a-204
(1)
|
Ensembl | 915 nt | ||
mRNA |
cpeb4a-206
(1)
|
Ensembl | 644 nt | ||
mRNA |
cpeb4a-207
(1)
|
Ensembl | 5,178 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-277C7 | ZFIN Curated Data | |
Contained in | BAC | DKEY-42A21 | ZFIN Curated Data | |
Encodes | cDNA | MGC:66166 | ZFIN Curated Data | |
Encodes | cDNA | MGC:193030 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001351720 (1) | 5031 nt | ||
Genomic | GenBank:CT025914 (1) | 222557 nt | ||
Polypeptide | UniProtKB:A0A8M3AHT9 (1) | 711 aa |
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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