Gene

cpeb4a

ID
ZDB-GENE-040426-1557
Name
cytoplasmic polyadenylation element binding protein 4a
Symbol
cpeb4a Nomenclature History
Previous Names
  • cpeb4
  • zgc:66166 (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to enable several functions, including mRNA 3'-UTR binding activity; mRNA regulatory element binding translation repressor activity; and translation factor activity, RNA binding. Predicted to be involved in several processes, including cellular response to glucose starvation; negative regulation of cytoplasmic translation; and response to ischemia. Predicted to act upstream of or within regulation of translation. Predicted to be located in dendrite; endoplasmic reticulum; and postsynaptic density. Predicted to be active in several cellular components, including neuron projection; nucleus; and synapse. Is expressed in cranial ganglion; neurons; olfactory placode; peripheral olfactory organ; and yolk syncytial layer. Orthologous to human CPEB4 (cytoplasmic polyadenylation element binding protein 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
No data available
Sequence Targeting Reagents
No data available
Human Disease
Associated With cpeb4a Human Ortholog
No data available
Associated With cpeb4a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR032296 Cytoplasmic polyadenylation element-binding protein, ZZ domain
Family IPR034819 Cytoplasmic polyadenylation element-binding protein
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
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Domain Details Per Protein
Protein Additional Resources Length CEBP, ZZ domain superfamily Cytoplasmic polyadenylation element-binding protein Cytoplasmic polyadenylation element-binding protein, ZZ domain Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA recognition motif domain
UniProtKB:A0A8M6Z9E0 InterPro 519
UniProtKB:F1QCY1 InterPro 703
UniProtKB:A0A8M6Z2L6 InterPro 511
UniProtKB:A0A8M3AHT9 InterPro 711
UniProtKB:B2GRL1 InterPro 635
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 14
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cpeb4a-201 (1) Ensembl 4,983 nt
mRNA cpeb4a-202 (1) Ensembl 5,031 nt
mRNA cpeb4a-204 (1) Ensembl 915 nt
mRNA cpeb4a-206 (1) Ensembl 644 nt
mRNA cpeb4a-207 (1) Ensembl 5,178 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-277C7ZFIN Curated Data
Contained inBACDKEY-42A21ZFIN Curated Data
EncodescDNAMGC:66166ZFIN Curated Data
EncodescDNAMGC:193030ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanCPEB45
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
MouseCpeb411
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
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