Gene

fzd6

ID
ZDB-GENE-040426-1451
Name
frizzled class receptor 6
Symbol
fzd6 Nomenclature History
Previous Names
  • zgc:65879
  • zgc:77440
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have Wnt-activated receptor activity. Involved in angiogenesis and embryonic cranial skeleton morphogenesis. Predicted to localize to integral component of membrane. Is expressed in head; nervous system; and pectoral fin. Human ortholog(s) of this gene implicated in nonsyndromic congenital nail disorder 1. Orthologous to human FZD6 (frizzled class receptor 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fzd6 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
nonsyndromic congenital nail disorder 1 Alliance Nail disorder, nonsyndromic congenital, 1 161050
Associated With fzd6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000539 Frizzled/Smoothened, transmembrane domain
Domain IPR017981 GPCR, family 2-like
Domain IPR020067 Frizzled domain
Domain IPR041770 Frizzled 6, cysteine-rich domain
Family IPR015526 Frizzled/secreted frizzled-related protein
Family IPR026543 Frizzled-6
Homologous_superfamily IPR036790 Frizzled cysteine-rich domain superfamily
Domain Details Per Protein
Protein Length Frizzled-6 Frizzled 6, cysteine-rich domain Frizzled cysteine-rich domain superfamily Frizzled domain Frizzled/secreted frizzled-related protein Frizzled/Smoothened, transmembrane domain GPCR, family 2-like
UniProtKB:Q6P0Y7 617
UniProtKB:A0A0G2L696 617
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations