Gene

tmem231

ID
ZDB-GENE-040426-1386
Name
transmembrane protein 231
Symbol
tmem231 Nomenclature History
Previous Names
  • chst5
  • zgc:64166 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to be involved in cilium assembly; regulation of protein localization; and smoothened signaling pathway. Predicted to act upstream of or within cell projection organization. Predicted to be located in cilium and plasma membrane. Predicted to be part of MKS complex. Predicted to be active in ciliary membrane and ciliary transition zone. Is expressed in blood; median fin fold; and periderm. Human ortholog(s) of this gene implicated in Joubert syndrome 20 and Meckel syndrome. Orthologous to human TMEM231 (transmembrane protein 231).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la014752TgTransgenic insertionUnknownUnknownDNA
sa6811Allele with one point mutationUnknownPremature StopENU
sa38131Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With tmem231 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Joubert syndrome 20 Alliance Joubert syndrome 20 614970
Meckel syndrome 11 615397
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Associated With tmem231 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR019306 Transmembrane protein 231
1 - 1 of 1
Domain Details Per Protein
Protein Additional Resources Length Transmembrane protein 231
UniProtKB:Q7T316 InterPro 309
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 25
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tmem231-201 (1) Ensembl 1,631 nt
mRNA tmem231-202 (1) Ensembl 847 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEYP-7F1ZFIN Curated Data
EncodescDNAMGC:64166ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanTMEM23116
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
MouseTmem2318
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
1 - 6 of 6
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