Gene

bokb

ID
ZDB-GENE-040426-1346
Name
BCL2 family apoptosis regulator BOK b
Symbol
bokb Nomenclature History
Previous Names
  • zBok2 (1)
  • zgc:64041
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have protein heterodimerization activity and protein homodimerization activity. Predicted to be involved in extrinsic apoptotic signaling pathway in absence of ligand and intrinsic apoptotic signaling pathway in response to DNA damage. Predicted to localize to mitochondrial outer membrane. Is expressed in several structures, including chordo neural hinge; nervous system; neural tube; ovary; and solid lens vesicle. Orthologous to human BOK (BCL2 family apoptosis regulator BOK).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bokb Human Ortholog
No data available
Associated With bokb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003093 Apoptosis regulator, Bcl-2 protein, BH4
Domain IPR046371 Bcl-2, Bcl-2 homology region 1-3
Family IPR002475 Bcl2-like
Family IPR026298 Bcl-2 family
Homologous_superfamily IPR036834 Bcl-2-like superfamily
Domain Details Per Protein
Protein Length Apoptosis regulator, Bcl-2 protein, BH4 Bcl-2, Bcl-2 homology region 1-3 Bcl-2 family Bcl2-like Bcl-2-like superfamily
UniProtKB:Q7T381 211
UniProtKB:B2GRX5 211
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations