ZFIN is now using GRCz12tu for Genomic Data
Gene
pias4b
- ID
- ZDB-GENE-040426-1298
- Name
- protein inhibitor of activated STAT, 4b
- Symbol
- pias4b Nomenclature History
- Previous Names
-
- pias4l
- wu:fi26h11
- zgc:63923
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable SUMO ligase activity; transcription coregulator activity; and transcription regulator inhibitor activity. Predicted to be involved in negative regulation of receptor signaling pathway via JAK-STAT; protein sumoylation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in chromatin and nucleoplasm. Is expressed in several structures, including gill; heart; integument; liver; and pleuroperitoneal region. Orthologous to human PIAS4 (protein inhibitor of activated STAT 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63923 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | PINIT domain | PINIT domain superfamily | SAP domain | SAP domain superfamily | Zinc finger, MIZ-type | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A2R8Q3K8 | InterPro | 445 | ||||||
| UniProtKB:F8W4B9 | InterPro | 485 | ||||||
| UniProtKB:A0AC58GID3 | InterPro | 403 | ||||||
| UniProtKB:A0AC58GIL3 | InterPro | 443 | ||||||
| UniProtKB:A0AC58GIP5 | InterPro | 306 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pias4b-202
(1)
|
Ensembl | 1,013 nt | ||
| mRNA |
pias4b-203
(1)
|
Ensembl | 1,663 nt | ||
| mRNA |
pias4b-204
(1)
|
Ensembl | 1,612 nt | ||
| ncRNA |
pias4b-003
(1)
|
Ensembl | 634 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers