Gene

ap4b1

ID
ZDB-GENE-040426-1284
Name
adaptor related protein complex 4 subunit beta 1
Symbol
ap4b1 Nomenclature History
Previous Names
  • ap4b1l
  • zgc:63878 (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have clathrin binding activity. Predicted to be involved in vesicle-mediated transport. Predicted to localize to clathrin adaptor complex. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 47. Orthologous to human AP4B1 (adaptor related protein complex 4 subunit beta 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ap4b1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hereditary spastic paraplegia 47 Alliance Spastic paraplegia 47, autosomal recessive 614066
Associated With ap4b1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminal
Domain IPR015151 Beta-adaptin appendage, C-terminal subdomain
Family IPR016342 AP-1/2/4 complex subunit beta
Family IPR026739 AP complex subunit beta
Homologous_superfamily IPR011989 Armadillo-like helical
Homologous_superfamily IPR012295 TBP domain superfamily
Homologous_superfamily IPR016024 Armadillo-type fold
Domain Details Per Protein
Protein Length AP-1/2/4 complex subunit beta AP complex subunit beta Armadillo-like helical Armadillo-type fold Beta-adaptin appendage, C-terminal subdomain Clathrin/coatomer adaptor, adaptin-like, N-terminal TBP domain superfamily
UniProtKB:F1QV11 729
UniProtKB:Q7T3G3 729
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations