Gene

pgm1

ID
ZDB-GENE-040426-1245
Name
phosphoglucomutase 1
Symbol
pgm1 Nomenclature History
Previous Names
  • zgc:63718
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to enable phosphoglucomutase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to act upstream of or within glucose metabolic process. Predicted to be active in cytosol. Is expressed in central nervous system; digestive system; myotome; notochord; and yolk syncytial layer. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation It; endometrial cancer; and teratoma. Orthologous to human PGM1 (phosphoglucomutase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pgm1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital disorder of glycosylation It Alliance Congenital disorder of glycosylation, type It 614921
Associated With pgm1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR016066 Alpha-D-phosphohexomutase, conserved site
Domain IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I
Domain IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II
Domain IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III
Family IPR005841 Alpha-D-phosphohexomutase superfamily
Family IPR045244 Phosphoglucomutase
Homologous_superfamily IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III
Homologous_superfamily IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily
Domain Details Per Protein
Protein Length Alpha-D-phosphohexomutase, alpha/beta/alpha domain I Alpha-D-phosphohexomutase, alpha/beta/alpha domain II Alpha-D-phosphohexomutase, alpha/beta/alpha domain III Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III Alpha-D-phosphohexomutase, conserved site Alpha-D-phosphohexomutase, C-terminal domain superfamily Alpha-D-phosphohexomutase superfamily Phosphoglucomutase
UniProtKB:Q7SXW7 561
UniProtKB:F1QF00 561
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations