Gene
traf3ip1
- ID
- ZDB-GENE-040426-1146
- Name
- TNF receptor-associated factor 3 interacting protein 1
- Symbol
- traf3ip1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable microtubule binding activity. Involved in regulation of microtubule cytoskeleton organization. Acts upstream of or within several processes, including cerebrospinal fluid circulation; nervous system development; and regulation of microtubule polymerization. Predicted to be located in cell projection; cytoplasm; and cytoskeleton. Predicted to be part of intraciliary transport particle B. Predicted to be active in axoneme and ciliary basal body. Human ortholog(s) of this gene implicated in Senior-Loken syndrome. Orthologous to human TRAF3IP1 (TRAF3 interacting protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 37 figures from 16 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Senior-Loken syndrome 9 | 616629 |
1 - 1 of 1
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | TRAF3-interacting protein 1 | TRAF3-interacting protein 1, C-terminal domain | TRAF3-interacting protein 1, N-terminal | TRAF3-interacting protein 1, N-terminal domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IR02 | InterPro | 644 | ||||
| UniProtKB:A0A8M2BJU3 | InterPro | 628 | ||||
| UniProtKB:A0A8M3AWA2 | InterPro | 643 | ||||
| UniProtKB:Q6PGZ3 | InterPro | 629 | ||||
| UniProtKB:A0A2R8PWH6 | InterPro | 637 |
1 - 5 of 9 Show all
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
traf3ip1-201
(1)
|
Ensembl | 2,241 nt | ||
| mRNA |
traf3ip1-202
(1)
|
Ensembl | 790 nt | ||
| mRNA |
traf3ip1-203
(1)
|
Ensembl | 1,935 nt | ||
| mRNA |
traf3ip1-204
(1)
|
Ensembl | 1,914 nt |
1 - 4 of 4
Interactions and Pathways
No data available
Plasmids
No data available