asns

ID

ZDB-GENE-040426-1091

Name

asparagine synthetase

Symbol

asns Nomenclature History

Previous Names

zgc:56605 (1)
zgc:76901

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable asparagine synthase (glutamine-hydrolyzing) activity. Predicted to be involved in asparagine biosynthetic process. Predicted to act upstream of or within amino acid biosynthetic process and glutamine metabolic process. Predicted to be active in cytosol. Is expressed in liver; male organism; and muscle. Orthologous to human ASNS (asparagine synthetase (glutamine-hydrolyzing)).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 7 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With asns Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Asparagine synthetase deficiency	615574

Associated With asns Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001962	Asparagine synthase
Domain	IPR017932	Glutamine amidotransferase type 2 domain
Domain	IPR033738	Asparagine synthase, N-terminal domain
Family	IPR006426	Asparagine synthase, glutamine-hydrolyzing
Family	IPR050795	Asparagine Synthetase
Homologous_superfamily	IPR014729	Rossmann-like alpha/beta/alpha sandwich fold
Homologous_superfamily	IPR029055	Nucleophile aminohydrolases, N-terminal