Gene

rnaseh2b

ID
ZDB-GENE-040426-1090
Name
ribonuclease H2, subunit B
Symbol
rnaseh2b Nomenclature History
Previous Names
  • zgc:56602
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have RNA-DNA hybrid ribonuclease activity. Predicted to be involved in RNA catabolic process and ribonucleotide metabolic process. Predicted to localize to nucleoplasm and ribonuclease H2 complex. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Is expressed in several structures, including alar plate midbrain region; blood; immature eye; nervous system; and ventral mesenchyme. Orthologous to human RNASEH2B (ribonuclease H2 subunit B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rnaseh2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Aicardi-Goutieres syndrome Alliance Aicardi-Goutieres syndrome 2 610181
Associated With rnaseh2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR019024 Ribonuclease H2 subunit B, wHTH domain
Family IPR040456 Ribonuclease H2 subunit B
Domain Details Per Protein
Protein Length Ribonuclease H2 subunit B Ribonuclease H2 subunit B, wHTH domain
UniProtKB:A0A8M2BF43 163
UniProtKB:Q7ZUH0 216
UniProtKB:A0A8M9QJJ8 306
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations