Gene
usf1
- ID
- ZDB-GENE-040426-1072
- Name
- upstream transcription factor 1
- Symbol
- usf1 Nomenclature History
- Previous Names
-
- zgc:56547
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in telencephalon. Human ortholog(s) of this gene implicated in cardiovascular system disease and type 2 diabetes mellitus. Orthologous to human USF1 (upstream transcription factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56547 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Hyperlipidemia, familial combined, susceptibility to} | 602491 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain | Upstream Stimulatory Factor |
|---|---|---|---|---|---|
| UniProtKB:Q7ZWC6 | InterPro | 309 | |||
| UniProtKB:A0A8M9QLB1 | InterPro | 303 | |||
| UniProtKB:A0A8M3B0Z9 | InterPro | 297 | |||
| UniProtKB:F1QUA1 | InterPro | 309 | |||
| UniProtKB:A0A8M9Q076 | InterPro | 293 | |||
| UniProtKB:A0A8M2B3M5 | InterPro | 288 | |||
| UniProtKB:A0A8M3APR4 | InterPro | 307 | |||
| UniProtKB:A0A8M2B4D0 | InterPro | 299 | |||
| UniProtKB:A0A8M2B4B2 | InterPro | 298 | |||
| UniProtKB:A0AB32T6B5 | InterPro | 296 | |||
| UniProtKB:A0AB32T846 | InterPro | 286 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
usf1-207
(1)
|
Ensembl | 1,450 nt | ||
| mRNA |
usf1-201
(1)
|
Ensembl | 1,492 nt | ||
| mRNA |
usf1-202
(1)
|
Ensembl | 710 nt | ||
| mRNA |
usf1-203
(1)
|
Ensembl | 402 nt | ||
| mRNA |
usf1-204
(1)
|
Ensembl | 931 nt | ||
| mRNA |
usf1-205
(1)
|
Ensembl | 579 nt | ||
| mRNA |
usf1-206
(1)
|
Ensembl | 832 nt | ||
| mRNA |
usf1-208
(1)
|
Ensembl | 765 nt | ||
| mRNA |
usf1-209
(1)
|
Ensembl | 805 nt | ||
| mRNA |
usf1-210
(1)
|
Ensembl | 838 nt | ||
| mRNA |
usf1-211
(1)
|
Ensembl | 2,868 nt |
Interactions and Pathways
No data available
Plasmids
No data available