ZFIN is now using GRCz12tu for Genomic Data
Gene
ptgesl
- ID
- ZDB-GENE-040426-1063
- Name
- prostaglandin E synthase 2-like
- Symbol
- ptgesl Nomenclature History
- Previous Names
-
- zgc:56527 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable several functions, including glutathione binding activity; heme binding activity; and prostaglandin-E synthase activity. Predicted to be involved in prostaglandin biosynthetic process. Predicted to act upstream of or within fatty acid biosynthetic process and prostaglandin metabolic process. Predicted to be located in Golgi membrane. Predicted to be active in mitochondrion. Is expressed in female organism; male organism; and reproductive system. Orthologous to human PTGES2 (prostaglandin E synthase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7140538 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR011767 | Glutaredoxin active site |
| Domain | IPR004045 | Glutathione S-transferase, N-terminal |
| Domain | IPR004046 | Glutathione S-transferase, C-terminal |
| Domain | IPR010987 | Glutathione S-transferase, C-terminal-like |
| Domain | IPR034335 | Prostaglandin E synthase 2, C-terminal |
| Family | IPR034334 | Prostaglandin E synthase 2 |
| Homologous_superfamily | IPR036249 | Thioredoxin-like superfamily |
| Homologous_superfamily | IPR036282 | Glutathione S-transferase, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Glutaredoxin active site | Glutathione S-transferase, C-terminal | Glutathione S-transferase, C-terminal domain superfamily | Glutathione S-transferase, C-terminal-like | Glutathione S-transferase, N-terminal | Prostaglandin E synthase 2 | Prostaglandin E synthase 2, C-terminal | Thioredoxin-like superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QDX0 | InterPro | 237 | ||||||||
| UniProtKB:A0A8M9PR36 | InterPro | 233 | ||||||||
| UniProtKB:Q7ZUC7 | InterPro | 377 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ptgesl-201
(1)
|
Ensembl | 1,989 nt | ||
| mRNA |
ptgesl-204
(1)
|
Ensembl | 1,475 nt | ||
| ncRNA |
ptgesl-002
(1)
|
Ensembl | 722 nt | ||
| ncRNA |
ptgesl-003
(1)
|
Ensembl | 728 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers