Gene

idh3a

ID
ZDB-GENE-040426-1007
Name
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
Symbol
idh3a Nomenclature History
Previous Names
  • zgc:56380 (1)
  • zgc:85631
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to enable isocitrate dehydrogenase (NAD+) activity. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Predicted to be active in mitochondrion. Is expressed in several structures, including alar plate midbrain region; mesoderm; musculature system; optic tectum; and pronephric duct. Human ortholog(s) of this gene implicated in retinitis pigmentosa 90. Orthologous to human IDH3A (isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With idh3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
retinitis pigmentosa 90 Alliance Retinitis pigmentosa 90 619007
Associated With idh3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site
Domain IPR024084 Isopropylmalate dehydrogenase-like domain
Family IPR004434 Isocitrate dehydrogenase NAD-dependent
Domain Details Per Protein
Protein Length Isocitrate dehydrogenase NAD-dependent Isocitrate/isopropylmalate dehydrogenase, conserved site Isopropylmalate dehydrogenase-like domain
UniProtKB:F1QI80 157
UniProtKB:A8E541 157
UniProtKB:Q6NV33 365
UniProtKB:Q7ZUJ7 365
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations