Gene

sarm1

ID
ZDB-GENE-040219-1
Name
sterile alpha and TIR motif containing 1
Symbol
sarm1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Enables NAD+ nucleosidase activity. Involved in NAD catabolic process. Acts upstream of or within several processes, including innate immune response; negative regulation of MyD88-independent toll-like receptor signaling pathway; and response to axon injury. Predicted to be located in axon; mitochondrion; and synapse. Orthologous to human SARM1 (sterile alpha and TIR motif containing 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sarm1 Human Ortholog
No data available
Associated With sarm1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
Domain IPR001660 Sterile alpha motif domain
Family IPR039184 Sterile alpha and TIR motif-containing protein 1
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily
Domain Details Per Protein
Protein Length Armadillo-type fold Sterile alpha and TIR motif-containing protein 1 Sterile alpha motif domain Sterile alpha motif/pointed domain superfamily Toll/interleukin-1 receptor homology (TIR) domain Toll/interleukin-1 receptor homology (TIR) domain superfamily
UniProtKB:F1QWA8 713
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations