Gene

trim71

ID

ZDB-GENE-040128-1

Name

tripartite motif containing 71, E3 ubiquitin protein ligase

Symbol

trim71 Nomenclature History

Previous Names

lin-41 (1)
lin41 (1)
cb205 (1)
fb93a12
sb:cb205
wu:fb93a12

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have miRNA binding activity; translation repressor activity; and ubiquitin protein ligase activity. Involved in embryonic body morphogenesis. Predicted to localize to P-body. Is expressed in several structures, including nervous system; neural tube; pectoral fin musculature; polster; and solid lens vesicle. Orthologous to human TRIM71 (tripartite motif containing 71).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb205 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Lin et al., 2007
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With trim71 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Hydrocephalus, congenital, 4	618667

Associated With trim71 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017907	Zinc finger, RING-type, conserved site
Domain	IPR000315	B-box-type zinc finger
Domain	IPR001841	Zinc finger, RING-type
Homologous_superfamily	IPR011042	Six-bladed beta-propeller, TolB-like
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR014756	Immunoglobulin E-set
Repeat	IPR001258	NHL repeat
Repeat	IPR001298	Filamin/ABP280 repeat
Repeat	IPR017868	Filamin/ABP280 repeat-like