Gene

slc24a5

ID
ZDB-GENE-031210-1
Name
solute carrier family 24 member 5
Symbol
slc24a5 Nomenclature History
Previous Names
  • gol-1 (3)
  • gol
  • golden-1 (3)
  • golden
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have calcium, potassium:sodium antiporter activity. Involved in melanocyte differentiation and melanocyte migration. Predicted to localize to integral component of membrane and trans-Golgi network. Human ortholog(s) of this gene implicated in oculocutaneous albinism type VI. Is expressed in female organism; male organism; melanocyte; and presumptive retinal pigmented epithelium. Orthologous to human SLC24A5 (solute carrier family 24 member 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
18 figures from 12 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc24a5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
oculocutaneous albinism type VI Alliance Albinism, oculocutaneous, type VI 113750
oculocutaneous albinism type VI Alliance [Skin/hair/eye pigmentation 4, fair/dark skin] 113750
Associated With slc24a5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004837 Sodium/calcium exchanger membrane region
Family IPR004481 Sodium/potassium/calcium exchanger
Family IPR030245 Sodium/potassium/calcium exchanger 5
Homologous_superfamily IPR044880 NCX, central ion-binding domain superfamily
Domain Details Per Protein
Protein Length NCX, central ion-binding domain superfamily Sodium/calcium exchanger membrane region Sodium/potassium/calcium exchanger Sodium/potassium/calcium exchanger 5
UniProtKB:B0V3S7 513
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations