Gene

slc24a5

ID

ZDB-GENE-031210-1

Name

solute carrier family 24 member 5

Symbol

slc24a5 Nomenclature History

Previous Names

gol-1 (3)
gol
golden-1 (3)
golden

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to enable calcium channel activity and calcium, potassium:sodium antiporter activity. Acts upstream of or within eye pigmentation; melanocyte differentiation; and melanocyte migration. Predicted to be located in membrane. Predicted to be active in trans-Golgi network. Is expressed in female organism; male organism; melanocyte; and presumptive retinal pigmented epithelium. Human ortholog(s) of this gene implicated in oculocutaneous albinism type VI. Orthologous to human SLC24A5 (solute carrier family 24 member 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 6 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 20 figures from 14 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc24a5 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
oculocutaneous albinism type VI	Alliance	Albinism, oculocutaneous, type VI	113750
oculocutaneous albinism type VI	Alliance	[Skin/hair/eye pigmentation 4, fair/dark skin]	113750