ZFIN is now using GRCz12tu for Genomic Data
Gene

si:dkey-222n6.2

ID
ZDB-GENE-031118-10
Name
si:dkey-222n6.2
Symbol
si:dkey-222n6.2 Nomenclature History
Previous Names
  • fd11e11
  • krtt2c8 (1)
  • wu:fd11e11
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Predicted to be located in cytoskeleton. Predicted to be active in keratin filament. Human ortholog(s) of this gene implicated in liver cirrhosis. Orthologous to human KRT77 (keratin 77); KRT8 (keratin 8); and KRT80 (keratin 80).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa9896Allele with one point mutationUnknownSplice SiteENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
sa14026Allele with one point mutationUnknownPremature StopENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
sa25387Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With si:dkey-222n6.2 Human Ortholog
No data available
Associated With si:dkey-222n6.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018039 Intermediate filament protein, conserved site
Domain IPR032444 Keratin type II head
Domain IPR039008 Intermediate filament, rod domain
Family IPR003054 Keratin, type II
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Domain Details Per Protein
Protein Additional Resources Length Intermediate filament protein, conserved site Intermediate filament, rod domain Keratin, type II Keratin type II head
UniProtKB:A0A8M1RNJ0 InterPro 376
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Transcripts
Genome Browsers
Genome Assembly: GRCz11Chromosome: 8
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA si:dkey-222n6.2-201 (1)
Ensembl
Ensembl 1,443 nt
ZFIN BLAST
ncRNA si:dkey-222n6.2-002 (1)
Ensembl
Ensembl 851 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-272M14ZFIN Curated Data
EncodesESTfd11e11
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Sequences
Genome Browsers
Genome Assembly: GRCz12tuChromosome: 8
Type Accession # Genome Assembly Length (nt/aa) Analysis
RNARefSeq:XM_003199050 (1)GRCz12tu3172 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:CU862015 (2)47305 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:A0A8M1RNJ0 (1)376 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
No data available
Citations
TSV
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Your Input Welcome
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