Gene
bicra
- ID
- ZDB-GENE-031116-2
- Name
- BRD4 interacting chromatin remodeling complex associated protein
- Symbol
- bicra Nomenclature History
- Previous Names
-
- gltscr1
- sb:cb888
- si:dkey-224e22.6
- wu:fc28g11
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Acts upstream of or within embryonic cranial skeleton morphogenesis. Predicted to be part of SWI/SNF complex. Is expressed in several structures, including hindbrain neural plate; intermediate cell mass of mesoderm; midbrain neural keel; nervous system; and presumptive telencephalon. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 12. Orthologous to human BICRA (BRD4 interacting chromatin remodeling complex associated protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb888 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Barish et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Coffin-Siris syndrome 12 | Alliance | Coffin-Siris syndrome 12 | 619325 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Chromatin-remodeling and transcription coactivator | GLTSCR protein, conserved domain |
|---|---|---|---|---|
| UniProtKB:A0A8M2B5V9 | InterPro | 1823 | ||
| UniProtKB:A0A8M1QHS7 | InterPro | 1801 | ||
| UniProtKB:A0A8M2B5S5 | InterPro | 1822 | ||
| UniProtKB:A0A8M2B5S4 | InterPro | 1761 | ||
| UniProtKB:A0AB32T7L6 | InterPro | 1800 | ||
| UniProtKB:A0AB32T8X2 | InterPro | 1739 | ||
| UniProtKB:A0AB32TCK4 | InterPro | 1760 |
Interactions and Pathways
No data available
Plasmids
No data available