Gene

disp1

ID
ZDB-GENE-030911-7
Name
dispatched homolog 1 (Drosophila)
Symbol
disp1 Nomenclature History
Previous Names
  • chameleon
  • con
  • helix
  • hlx
  • zgc:111866
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Acts upstream of or within several processes, including embryonic cranial skeleton morphogenesis; muscle cell fate specification; and nervous system development. Predicted to be active in membrane. Is expressed in mouth; neuroectoderm; oral region; pharyngeal endoderm; and pharynx. Orthologous to human DISP1 (dispatched RND transporter family member 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
29 figures from 11 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With disp1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Holoprosencephaly 10 621143
1 - 1 of 1
Associated With disp1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000731 Sterol-sensing domain
Domain IPR004869 Membrane transport protein MMPL domain
Domain IPR053958 HMGCR/SNAP/NPC1-like, sterol-sensing domain
Family IPR052081 Dispatched hedgehog regulator
1 - 4 of 4
Domain Details Per Protein
Protein Additional Resources Length Dispatched hedgehog regulator HMGCR/SNAP/NPC1-like, sterol-sensing domain Membrane transport protein MMPL domain Sterol-sensing domain
UniProtKB:Q6R5J2 InterPro 1464
UniProtKB:F1QHY7 InterPro 1464
1 - 2 of 2
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA disp1-201 (1) Ensembl 4,623 nt
mRNA disp1-202 (1) Ensembl 4,504 nt
1 - 2 of 2
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations