Gene
tktb
- ID
- ZDB-GENE-030909-13
- Name
- transketolase b
- Symbol
- tktb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable thiamine pyrophosphate binding activity and transketolase activity. Predicted to be located in cytoplasm. Is expressed in several structures, including alar plate midbrain region; digestive system; eye; midbrain; and yolk. Orthologous to several human genes including TKTL2 (transketolase like 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb860 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Short stature, developmental delay, and congenital heart defects | 617044 |
1 - 1 of 1
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Thiamin diphosphate-binding fold | Transketolase binding site | Transketolase, C-terminal domain | Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II | Transketolase-like | Transketolase-like, pyrimidine-binding domain | Transketolase, N-terminal |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6PHI8 | InterPro | 625 | |||||||
| UniProtKB:A0A8M9PWD4 | InterPro | 579 |
1 - 2 of 2
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available