Gene

ncor2

ID
ZDB-GENE-030616-81
Name
nuclear receptor corepressor 2
Symbol
ncor2 Nomenclature History
Previous Names
  • gb:be017685
  • si:bz71m17.2
  • smrt (1)
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have several functions, including DNA binding activity; histone deacetylase binding activity; and transcription corepressor activity. Involved in hematopoietic stem cell differentiation; macrophage differentiation; and neutrophil differentiation. Predicted to localize to histone deacetylase complex; nuclear chromatin; and transcriptional repressor complex. Human ortholog(s) of this gene implicated in osteoarthritis. Is expressed in several structures, including anterior axial hypoblast; cardiovascular system; central nervous system; eye; and pleuroperitoneal region. Orthologous to human NCOR2 (nuclear receptor corepressor 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ncor2 Human Ortholog
No data available
Associated With ncor2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001005 SANT/Myb domain
Domain IPR017884 SANT domain
Domain IPR017930 Myb domain
Domain IPR031557 N-CoR, GPS2-interacting domain
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox-like domain superfamily Myb domain N-CoR, GPS2-interacting domain SANT domain SANT/Myb domain
UniProtKB:F1R8Z8 1989
UniProtKB:E7FF48 2315
UniProtKB:G3GBZ0 2262
UniProtKB:F1R8E1 1999
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations