ZFIN is now using GRCz12tu for Genomic Data
Gene
tap2a
- ID
- ZDB-GENE-030616-245
- Name
- transporter associated with antigen processing, subunit type a
- Symbol
- tap2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ABC-type peptide transporter activity. Acts upstream of or within response to cadmium ion. Predicted to be part of MHC class I peptide loading complex. Predicted to be active in membrane. Is expressed in brain; gill; liver; and musculature system. Human ortholog(s) of this gene implicated in several diseases, including aspirin-induced respiratory disease; autoimmune disease (multiple); cervical cancer (multiple); dengue hemorrhagic fever; and systemic scleroderma (multiple). Orthologous to human TAP2 (transporter 2, ATP binding cassette subfamily B member).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Gonzalez et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017871 | ABC transporter-like, conserved site |
| Domain | IPR003439 | ABC transporter-like, ATP-binding domain |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR011527 | ABC transporter type 1, transmembrane domain |
| Family | IPR039421 | Type 1 protein exporter |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | AAA+ ATPase domain | ABC transporter-like, ATP-binding domain | ABC transporter-like, conserved site | ABC transporter type 1, transmembrane domain | ABC transporter type 1, transmembrane domain superfamily | P-loop containing nucleoside triphosphate hydrolase | Type 1 protein exporter |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q801W2 | InterPro | 725 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA | abcb3l1-001 (1) | Havana | 2,178 nt | ||
| mRNA |
tap2a-201
(1)
|
Ensembl | 3,190 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers