Gene

cnp

ID
ZDB-GENE-030521-29
Name
2',3'-cyclic nucleotide 3' phosphodiesterase
Symbol
cnp Nomenclature History
Previous Names
  • CNPase (1)
  • cnpl
  • fd21d08
  • fi37a10
  • sb:cb662 (1)
  • si:ch73-158e11.4
  • wu:fd21d08
  • wu:fd44a05
  • wu:fi35d08
  • wu:fi37a10
  • zRICH (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Exhibits 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity. Involved in axon regeneration. Localizes to cytosol. Human ortholog(s) of this gene implicated in multiple sclerosis and schizophrenia. Is expressed in several structures, including axis; cardiovascular system; central nervous system; hindbrain neural plate; and neural tube. Orthologous to human CNP (2',3'-cyclic nucleotide 3' phosphodiesterase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cnp Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hypomyelinating leukodystrophy 20 Alliance ?Leukodystrophy, hypomyelinating, 20 619071
Associated With cnp Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR047325 Cyclic nucleotide phosphodiesterase, catalytic domain
Family IPR008431 Cyclic nucleotide phosphodiesterase
Homologous_superfamily IPR009097 Cyclic phosphodiesterase
Domain Details Per Protein
Protein Length Cyclic nucleotide phosphodiesterase Cyclic nucleotide phosphodiesterase, catalytic domain Cyclic phosphodiesterase
UniProtKB:A0A8M3B0U8 424
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations