Gene

prl

ID

ZDB-GENE-030513-1

Name

prolactin

Symbol

prl Nomenclature History

Previous Names

prl1 (1)
zgc:110500

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have hormone activity. Involved in ion homeostasis; multicellular organismal response to stress; and negative regulation of apoptotic process. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in carotid artery disease. Is expressed in adenohypophyseal placode; female organism; hypophysis; male organism; and peptide hormone secreting cell. Orthologous to human PRL (prolactin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

57 figures from 31 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 8 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With prl Human Ortholog

No data available

Associated With prl Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018116	Somatotropin hormone, conserved site
Family	IPR001400	Somatotropin/prolactin
Homologous_superfamily	IPR009079	Four-helical cytokine-like, core