ZFIN is now using GRCz12tu for Genomic Data
Gene
p2rx1
- ID
- ZDB-GENE-030319-1
- Name
- purinergic receptor P2X, ligand-gated ion channel, 1
- Symbol
- p2rx1 Nomenclature History
- Previous Names
-
- zP2X1_tv1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables extracellularly ATP-gated monoatomic cation channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to act upstream of or within monoatomic cation transmembrane transport and response to ATP. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in hypothalamus and midbrain. Orthologous to human P2RX1 (purinergic receptor P2X 1).
- Genome Resources
- Note
-
The AAQ21194 sequence was non-functional because of a substitution of serine 239 with a tyrosine as shown in ZDB-PUB-081022-21
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | ATP P2X receptor, conserved site | P2X1 purinoceptor | P2X purinoreceptor | P2X purinoreceptor extracellular domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q7SZM0 | InterPro | 398 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers