copb1

ID

ZDB-GENE-030219-38

Name

COPI coat complex subunit beta 1

Symbol

copb1 Nomenclature History

Previous Names

hap
happy
id:ibd5034
wu:fc66c05
zgc:92482

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable structural molecule activity. Acts upstream of or within notochord development and somite development. Predicted to be located in Golgi membrane and cytoplasmic vesicle. Predicted to be part of COPI vesicle coat. Is expressed in axis; brain; neural rod; and notochord. Orthologous to human COPB1 (COPI coat complex subunit beta 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7150894 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 12 figures from 4 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With copb1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Baralle-Macken syndrome	619255

Associated With copb1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002553	Clathrin/coatomer adaptor, adaptin-like, N-terminal
Domain	IPR011710	Coatomer beta subunit, C-terminal
Domain	IPR029446	Coatomer beta subunit, appendage platform domain
Family	IPR016460	Coatomer beta subunit (COPB1)
Homologous_superfamily	IPR011989	Armadillo-like helical
Homologous_superfamily	IPR016024	Armadillo-type fold