Gene
rreb1a
- ID
- ZDB-GENE-030219-137
- Name
- ras responsive element binding protein 1a
- Symbol
- rreb1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within regulation of glucose metabolic process. Predicted to be active in nucleus. Is expressed in notochord; somite; and tail bud. Orthologous to human RREB1 (ras responsive element binding protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Kudoh et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
sa24433 | Allele with one point mutation | Unknown | Splice Site | ENU |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Ras-responsive element-binding protein 1 | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
---|---|---|---|---|---|
UniProtKB:F1R609 | InterPro | 1689 | |||
UniProtKB:A0A2R8QDP4 | InterPro | 1675 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
rreb1a-201
(1)
|
Ensembl | 8,432 nt | ||
mRNA |
rreb1a-202
(1)
|
Ensembl | 875 nt | ||
mRNA |
rreb1a-203
(1)
|
Ensembl | 8,503 nt | ||
mRNA |
rreb1a-204
(1)
|
Ensembl | 7,846 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-266D19 | ZFIN Curated Data | |
Encodes | EST | ibd1338 |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_002666582 (1) | 7944 nt | ||
Genomic | GenBank:BX294164 (1) | 177516 nt | ||
Polypeptide | UniProtKB:F1R609 (1) | 1689 aa |
- Mattis, K.K., Krentz, N.A.J., Metzendorf, C., Abaitua, F., Spigelman, A.F., Sun, H., Ikle, J.M., Thaman, S., Rottner, A.K., Bautista, A., Mazzaferro, E., Perez-Alcantara, M., Manning Fox, J.E., Torres, J.M., Wesolowska-Andersen, A., Yu, G.Z., Mahajan, A., Larsson, A., MacDonald, P.E., Davies, B., den Hoed, M., Gloyn, A.L. (2023) Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression. Diabetologia. 66(4):674-694
- Liu, Y., Kassack, M.E., McFaul, M.E., Christensen, L.N., Siebert, S., Wyatt, S.R., Kamei, C.N., Horst, S., Arroyo, N., Drummond, I.A., Juliano, C.E., Draper, B.W. (2022) Single-cell transcriptome reveals insights into the development and function of the zebrafish ovary. eLIFE. 11:
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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