Gene
slc26a10
- ID
- ZDB-GENE-030131-9845
- Name
- solute carrier family 26 member 10
- Symbol
- slc26a10 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable inorganic anion transmembrane transporter activity and organic anion transmembrane transporter activity. Predicted to be involved in chloride transmembrane transport and sulfate transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in otic placode and otic vesicle. Orthologous to human SLC26A10P (solute carrier family 26 member 10, pseudogene).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb448 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| CRISPR1-slc26a10 | Lin et al., 2025 | |
| CRISPR2-slc26a10 | Lin et al., 2025 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | SLC26A/SulP transporter | SLC26A/SulP transporter domain | STAS domain | STAS domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1QQZ8 | InterPro | 690 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc26a10-201
(1)
|
Ensembl | 2,297 nt | ||
| mRNA |
slc26a10-202
(1)
|
Ensembl | 2,025 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-228G21 | ZFIN Curated Data | |
| Encodes | EST | cb448 | Thisse et al., 2001 | |
| Encodes | EST | fb74a09 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_001921731 (1) | 3656 nt | ||
| Genomic | GenBank:BX663515 (1) | 224215 nt | ||
| Polypeptide | UniProtKB:A0A8M1QQZ8 (1) | 690 aa |
- Lin, S.J., Huang, K., Petree, C., Qin, W., Varshney, P., Varshney, G.K. (2025) Optimizing gRNA selection for high-penetrance F0 CRISPR screening for interrogating disease gene function. Nucleic acids research. 53:
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Liu, F., Xia, W., Hu, J., Wang, Y., Yang, F., Sun, S., Zhang, J., Jiang, N., Wang, H., Tian, W., Wang, X., Ma, D. (2015) Solute Carrier Family 26 Member a2 (slc26a2) Regulates Otic Development and Hair Cell Survival in Zebrafish. PLoS One. 10:e0136832
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