ZFIN is now using GRCz12tu for Genomic Data
Gene
ftsj3
- ID
- ZDB-GENE-030131-9828
- Name
- FtsJ RNA 2'-O-methyltransferase 3
- Symbol
- ftsj3 Nomenclature History
- Previous Names
-
- ftsj
- cb410 (1)
- sb:cb410
- wu:fa08a09
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable rRNA (guanine) methyltransferase activity and rRNA (uridine-2'-O-)-methyltransferase activity. Predicted to be involved in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and rRNA methylation. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleolus. Is expressed in several structures, including digestive system; immature eye; mesoderm; midbrain; and musculature system. Orthologous to human FTSJ3 (FtsJ RNA 2'-O-methyltransferase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb410 (20 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa43744 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002877 | Ribosomal RNA methyltransferase, FtsJ domain |
| Domain | IPR012920 | Ribosomal RNA methyltransferase, SPB1-like, C-terminal |
| Domain | IPR024576 | Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 |
| Family | IPR015507 | Ribosomal RNA large subunit methyltransferase E |
| Family | IPR028589 | AdoMet-dependent rRNA methyltransferase SPB1-like |
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Domain Details Per Protein
| Protein | Additional Resources | Length | AdoMet-dependent rRNA methyltransferase SPB1-like | Ribosomal RNA large subunit methyltransferase E | Ribosomal RNA large subunit methyltransferase RlmE | Ribosomal RNA methyltransferase, FtsJ domain | Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 | Ribosomal RNA methyltransferase, SPB1-like, C-terminal | S-adenosyl-L-methionine-dependent methyltransferase superfamily |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IQB8 | InterPro | 838 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | Fosmid | CH1073-188M7 | ZFIN Curated Data | |
| Encodes | EST | cb410 | Thisse et al., 2001 | |
| Encodes | EST | fa08a09 |
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| Type | Accession # | Genome Assembly | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001305468 (1) | 2690 nt | ||
| Genomic | GenBank:CU498832 (2) | 39129 nt | ||
| Polypeptide | UniProtKB:A0A0R4IQB8 (1) | 838 aa |