Gene

lama5

ID
ZDB-GENE-030131-9823
Name
laminin, alpha 5
Symbol
lama5 Nomenclature History
Previous Names
  • fra (1)
  • cb402 (1)
  • fransen (1)
  • im:7138247
  • sb:cb402
  • unm m538
  • wu:fb81a10
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have integrin binding activity. Involved in cell-cell adhesion; fin morphogenesis; and protein localization. Predicted to localize to laminin-5 complex. Is expressed in several structures, including axial mesoderm; endoderm; nervous system; pectoral fin bud; and pharynx. Orthologous to human LAMA5 (laminin subunit alpha 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
32 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
18 figures from 6 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lama5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Nephrotic syndrome, type 26 620049
Associated With lama5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000034 Laminin IV
Domain IPR000742 EGF-like domain
Domain IPR001791 Laminin G domain
Domain IPR002049 Laminin-type EGF domain
Domain IPR008211 Laminin, N-terminal
Domain IPR009254 Laminin alpha, domain I
Domain IPR010307 Laminin domain II
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Domain Details Per Protein
Protein Length Concanavalin A-like lectin/glucanase domain superfamily EGF-like domain Laminin alpha, domain I Laminin domain II Laminin G domain Laminin IV Laminin, N-terminal Laminin-type EGF domain
UniProtKB:D7PSA0 3664
UniProtKB:F1QKW3 3664
UniProtKB:Q2Q1W5 3664
UniProtKB:Q5BLH6 526
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations