ZFIN is now using GRCz12tu for Genomic Data

Gene

eif5

ID

ZDB-GENE-030131-975

Name

eukaryotic translation initiation factor 5

Symbol

eif5 Nomenclature History

Previous Names

fb37c12
fb54h04
wu:fb37c12
wu:fb54h04
zgc:77026 (1)

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable GDP-dissociation inhibitor activity; eukaryotic initiation factor eIF2 binding activity; and translation initiation factor activity. Predicted to be involved in formation of cytoplasmic translation initiation complex. Predicted to act upstream of or within translational initiation. Predicted to be active in cytosol. Is expressed in lens. Orthologous to human EIF5 (eukaryotic translation initiation factor 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56606 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With eif5 Human Ortholog

No data available

Associated With eif5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002735	Translation initiation factor IF2/IF5 domain
Domain	IPR003307	W2 domain
Family	IPR045196	Translation initiation factor IF2/IF5
Homologous_superfamily	IPR016024	Armadillo-type fold
Homologous_superfamily	IPR016189	Translation initiation factor IF2/IF5, N-terminal
Homologous_superfamily	IPR016190	Translation initiation factor IF2/IF5, zinc-binding

Domain Details Per Protein

Protein	Additional Resources	Length	Armadillo-type fold	Translation initiation factor IF2/IF5	Translation initiation factor IF2/IF5 domain	Translation initiation factor IF2/IF5, N-terminal	Translation initiation factor IF2/IF5, zinc-binding	W2 domain
UniProtKB:Q7ZWA9	InterPro	429

Transcripts

Genome Browsers

NCBI Map Viewer

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	eif5-201 (1) Ensembl	Ensembl	2,090 nt	Select Tool ZFIN BLAST
mRNA	eif5-203 (1) Ensembl	Ensembl	754 nt	Select Tool ZFIN BLAST
mRNA	eif5-205 (1) Ensembl	Ensembl	741 nt	Select Tool ZFIN BLAST
mRNA	eif5-206 (1) Ensembl	Ensembl	986 nt	Select Tool ZFIN BLAST
mRNA	eif5-207 (1) Ensembl	Ensembl	1,982 nt	Select Tool ZFIN BLAST
mRNA	eif5-208 (1) Ensembl	Ensembl	4,391 nt	Select Tool ZFIN BLAST
mRNA	eif5-209 (1) Ensembl	Ensembl	1,620 nt	Select Tool ZFIN BLAST
ncRNA	eif5-003 (1) Ensembl	Ensembl	832 nt	Select Tool ZFIN BLAST
ncRNA	eif5-005 (1) Ensembl	Ensembl	846 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations