Gene

ccne2

ID
ZDB-GENE-030131-9689
Name
cyclin E2
Symbol
ccne2 Nomenclature History
Previous Names
  • cb165 (1)
  • sb:cb165
  • zgc:86724
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Is predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Involved in G1/S transition of mitotic cell cycle and regulation of cyclin-dependent protein serine/threonine kinase activity. Acts upstream of or within regulation of cell cycle. Predicted to be part of cyclin E1-CDK2 complex and cyclin E2-CDK2 complex. Is expressed in brain; digestive system; head; and proliferative region. Human ortholog(s) of this gene implicated in castration-resistant prostate carcinoma. Orthologous to human CCNE2 (cyclin E2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ccne2 Human Ortholog
No data available
Associated With ccne2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004367 Cyclin, C-terminal domain
Domain IPR006671 Cyclin, N-terminal
Domain IPR013763 Cyclin-like
Family IPR028858 Cyclin E
Family IPR039361 Cyclin
Homologous_superfamily IPR036915 Cyclin-like superfamily
Domain Details Per Protein
Protein Length Cyclin Cyclin, C-terminal domain Cyclin E Cyclin-like Cyclin-like superfamily Cyclin, N-terminal
UniProtKB:A0A0R4IZL9 50
UniProtKB:Q6IQK5 392
UniProtKB:A0A2R8QID0 388
UniProtKB:A9JTA5 357
UniProtKB:A0A0R4IK54 392
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations