Gene

ogt.1

ID
ZDB-GENE-030131-9631
Name
O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
Symbol
ogt.1 Nomenclature History
Previous Names
  • ogt
  • ogta (1)
  • copy I (1)
  • fm81g08
  • wu:fc12b01
  • wu:fm81g08
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Enables protein N-acetylglucosaminyltransferase activity. Acts upstream of or within protein O-linked glycosylation. Is expressed in brain; caudal fin; and trunk. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 106. Orthologous to human OGT (O-linked N-acetylglucosamine (GlcNAc) transferase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Webster et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa18601Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
sa42376Allele with one point mutationUnknownSplice SiteENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
1 - 2 of 2
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-ogt.1
    		 (2)
    CRISPR2-ogt.1
      		 (2)
      MO1-ogt.1N/A (2)
      1 - 3 of 3
      Show
      Human Disease
      Associated With ogt.1 Human Ortholog
      Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
      non-syndromic X-linked intellectual disability 106 Alliance Intellectual developmental disorder, X-linked 106 300997
      1 - 1 of 1
      Associated With ogt.1 Via Experimental Models
      No data available
      Gene Ontology
      Protein Domains
      Domain, Family, and Site Summary
      Type InterPro ID Name
      Domain IPR029489 O-GlcNAc transferase, C-terminal
      Family IPR037919 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit
      Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
      Repeat IPR019734 Tetratricopeptide repeat
      1 - 4 of 4
      Domain Details Per Protein
      Protein Additional Resources Length O-GlcNAc transferase, C-terminal Tetratricopeptide-like helical domain superfamily Tetratricopeptide repeat UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit
      UniProtKB:A0A0R4IVJ0 InterPro 1102
      UniProtKB:A0A8M3B8G4 InterPro 886
      UniProtKB:Q5GA11 InterPro 1046
      UniProtKB:Q5GA12 InterPro 1052
      UniProtKB:Q5GA13 InterPro 1062
      1 - 5 of 6 Show all
      Transcripts
      Genome Browsers
      Type Name Annotation Method Has Havana Data Length (nt) Analysis
      mRNA ogt.1-207 (1)
      Ensembl
      		Ensembl 498 nt
      ZFIN BLAST
      mRNA ogt.1-208 (1)
      Ensembl
      		Ensembl 3,189 nt
      ZFIN BLAST
      mRNA ogt.1-210 (1)
      Ensembl
      		Ensembl 6,832 nt
      ZFIN BLAST
      mRNA ogt.1-212 (1)
      Ensembl
      		Ensembl 4,195 nt
      ZFIN BLAST
      mRNA ogt.1-213 (1)
      Ensembl
      		Ensembl 3,159 nt
      ZFIN BLAST
      1 - 5 of 11 Show all
      Interactions and Pathways
      No data available
      Antibodies
      No data available
      Plasmids
      No data available
      Constructs
      No data available
      Marker Relationships
      Relationship Marker Type Marker Accession Numbers Citations
      Contained inBACDKEY-102M7ZFIN Curated Data
      EncodesESTfc12b01ZFIN Curated Data
      EncodesESTfm81g08
      EncodescDNAMGC:162075ZFIN Curated Data
      EncodescDNAMGC:195351ZFIN Curated Data
      1 - 5 of 5
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      Sequences
      Orthology
      Comparative Orthology
      Alliance
      Gene Tree
      Ensembl
      Citations
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