Gene

pde4ba

ID

ZDB-GENE-030131-9570

Name

phosphodiesterase 4B, cAMP-specific a

Symbol

pde4ba Nomenclature History

Previous Names

pde4b
fj87g04
wu:fj87g04

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have 3',5'-cyclic-AMP phosphodiesterase activity and ion channel binding activity. Predicted to be involved in signal transduction. Predicted to localize to cytosol. Is expressed in oocyte and oocyte stage V. Orthologous to human PDE4B (phosphodiesterase 4B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Pang et al., 2018

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pde4ba Human Ortholog

No data available

Associated With pde4ba Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR023174	3'5'-cyclic nucleotide phosphodiesterase, conserved site
Domain	IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
Domain	IPR003607	HD/PDEase domain
Domain	IPR040844	Phosphodiesterase 4 upstream conserved regions (UCR)
Family	IPR023088	3'5'-cyclic nucleotide phosphodiesterase
Homologous_superfamily	IPR036971	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily

Domain Details Per Protein

Protein	Length	3'5'-cyclic nucleotide phosphodiesterase	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily	3'5'-cyclic nucleotide phosphodiesterase, conserved site	HD/PDEase domain	Phosphodiesterase 4 upstream conserved regions (UCR)
UniProtKB:A0A8M9PRG2 InterPro	94
UniProtKB:A0A8M9Q0L5 InterPro	713
UniProtKB:A0A8M9PYP3 InterPro	507
UniProtKB:A0A8M2BD66 InterPro	501
UniProtKB:A0A8M9PMW2 InterPro	734

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pde4ba-203 (1) Ensembl	Havana	4512 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	pde4ba-204 (1) Ensembl	Havana	919 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	pde4ba-205 (1) Ensembl	Havana	1785 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	pde4ba-002 (1) Ensembl	Havana	494 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations