Gene

smg9

ID
ZDB-GENE-030131-9385
Name
SMG9 nonsense mediated mRNA decay factor
Symbol
smg9 Nomenclature History
Previous Names
  • fj67f05
  • si:dkey-79d12.3
  • wu:fj67f05 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to be involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Orthologous to human SMG9 (SMG9 nonsense mediated mRNA decay factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Lawir et al., 2020
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
oi7Allele with one deletionExon 1UnknownCRISPR
sa2858Allele with one point mutationUnknownSplice SiteENU
sa36124Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-smg9 (2)
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Human Disease
Associated With smg9 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Heart and brain malformation syndrome 616920
Neurodevelopmental disorder with intention tremor, pyramidal signs, dyspraxia, and ocular anomalies 619995
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Associated With smg9 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR019354 Nonsense-mediated mRNA decay factor SMG8-like
Family IPR039177 Nonsense-mediated mRNA decay factor SMG9
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
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Domain Details Per Protein
Protein Additional Resources Length Nonsense-mediated mRNA decay factor SMG8-like Nonsense-mediated mRNA decay factor SMG9 P-loop containing nucleoside triphosphate hydrolase
UniProtKB:E7F7F6 InterPro 505
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 16
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA smg9-201 (1)
Ensembl
Ensembl 1,518 nt
ZFIN BLAST
mRNA smg9-202 (1)
Ensembl
Ensembl 2,342 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-79D12ZFIN Curated Data
EncodesESTfj67f05
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_001923780 (1)2314 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:BX005256 (1)199468 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:E7F7F6 (1)505 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanSMG919
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseSmg97
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
TSV
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