Gene
zgc:153867
- ID
- ZDB-GENE-030131-9170
- Name
- zgc:153867
- Symbol
- zgc:153867 Nomenclature History
- Previous Names
-
- fb02e09
- hm:zehn1575
- wu:fa98e09
- wu:fb02e09
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to be a structural constituent of muscle. Predicted to be part of myosin II complex. Orthologous to several human genes including MYL6 (myosin light chain 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chen et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Calmodulin/Myosin light chain/Troponin C-like | EF-hand domain | EF-hand domain pair |
|---|---|---|---|---|---|
| UniProtKB:Q6TNS5 | InterPro | 151 | |||
| UniProtKB:E9QG86 | InterPro | 151 | |||
| UniProtKB:A0A8M9PWC9 | InterPro | 209 | |||
| UniProtKB:A0A8M6Z3P2 | InterPro | 209 | |||
| UniProtKB:A0A8M2B9A6 | InterPro | 197 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
myl6 (1 of many)-208
(1)
|
Ensembl | 1,092 nt | ||
| mRNA |
zgc:153867-201
(1)
|
Ensembl | 612 nt | ||
| mRNA |
zgc:153867-202
(1)
|
Ensembl | 813 nt | ||
| mRNA |
zgc:153867-203
(1)
|
Ensembl | 784 nt | ||
| mRNA |
zgc:153867-204
(1)
|
Ensembl | 850 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-149I8 | ZFIN Curated Data | |
| Encodes | EST | fa98e09 | ZFIN Curated Data | |
| Encodes | EST | fb02e09 | ||
| Encodes | EST | zehn1575 | ||
| Encodes | cDNA | MGC:153867 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:192071 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_213638 (1) | 1012 nt | ||
| Genomic | GenBank:CR381567 (1) | 142417 nt | ||
| Polypeptide | UniProtKB:A0A8M6Z3P2 (1) | 209 aa |
No data available
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Frohnhöfer, H.G., Geiger-Rudolph, S., Pattky, M., Meixner, M., Huhn, C., Maischein, H.M., Geisler, R., Gehring, I., Maderspacher, F., Nüsslein-Volhard, C., Irion, U. (2016) Spermidine, but not spermine, is essential for pigment pattern formation in zebrafish. Biology Open. 5(6):736-44
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Zhao, S., Xie, P., Li, G., Jun, C., Cai, Y., Xiong, Q., and Zhao, Y. (2012) The proteomic study on cellular responses of the testes of zebrafish (Danio rerio) exposed to microcystin-RR. Proteomics. 12(2):300-312
- Zheng, W., Wang, Z., Collins, J.E., Andrews, R.M., Stemple, D., and Gong, Z. (2011) Comparative transcriptome analyses indicate molecular homology of zebrafish swimbladder and Mammalian lung. PLoS One. 6(8):e24019
- Chen, Z., Huang, W., Dahme, T., Rottbauer, W., Ackerman, M.J., and Xu, X. (2008) Depletion of Zebrafish Essential and Regulatory Myosin Light Chains Reduces Cardiac Function Through Distinct Mechanisms. Cardiovascular research. 79(1):97-108
- Ninkovic, J., Stigloher, C., Lillesaar, C., and Bally-Cuif, L. (2008) Gsk3{beta}/PKA and Gli1 regulate the maintenance of neural progenitors at the midbrain-hindbrain boundary in concert with E(Spl) factor activity. Development (Cambridge, England). 135(18):3137-3148
- Buckles, G.R., Thorpe, C.J., Ramel, M.C., and Lekven, A.C. (2004) Combinatorial Wnt control of zebrafish midbrain-hindbrain boundary formation. Mechanisms of Development. 121(5):437-447
- Linney, E., Dobbs-McAuliffe, B., Sajadi, H., and Malek, R.L. (2004) Microarray gene expression profiling during the segmentation phase of zebrafish development. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 138(3):351-362
- Riley, B.B., Chiang, M.Y., Storch, E.M., Heck, R., Buckles, G.R., and Lekven, A.C. (2004) Rhombomere boundaries are Wnt signaling centers that regulate metameric patterning in the zebrafish hindbrain. Developmental Dynamics : an official publication of the American Association of Anatomists. 231(2):278-291
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