Gene

ndc80

ID
ZDB-GENE-030131-904
Name
NDC80 kinetochore complex component
Symbol
ndc80 Nomenclature History
Previous Names
  • HEC (highly expressed in cancer) (1)
  • kntc2l (1)
  • wu:fb52e02
  • zgc:111801
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to be involved in attachment of mitotic spindle microtubules to kinetochore; mitotic spindle organization; and positive regulation of mitotic cell cycle spindle assembly checkpoint. Predicted to localize to Ndc80 complex and condensed nuclear chromosome kinetochore. Is expressed in proliferative region. Orthologous to human NDC80 (NDC80 kinetochore complex component).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ndc80 Human Ortholog
No data available
Associated With ndc80 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR040967 Domain of unknown function DUF5595
Family IPR005550 Kinetochore protein Ndc80
Homologous_superfamily IPR038273 Ndc80 domain superfamily
Domain Details Per Protein
Protein Length Domain of unknown function DUF5595 Kinetochore protein Ndc80 Ndc80 domain superfamily
UniProtKB:Q6DRJ7 632
UniProtKB:E9QBF3 173
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations