Gene
rpl21
- ID
- ZDB-GENE-030131-8512
- Name
- ribosomal protein L21
- Symbol
- rpl21 Nomenclature History
- Previous Names
-
- wu:fb13h07
- wu:fc74e02
- zgc:86669
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to be a structural constituent of ribosome. Predicted to act upstream of or within translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in endodermal cell; intestine; liver; and pancreas. Human ortholog(s) of this gene implicated in hypotrichosis 12. Orthologous to human RPL21 (ribosomal protein L21).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6906305 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypotrichosis 12 | Alliance | Hypotrichosis 12 | 615885 |
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Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018259 | Large ribosomal subunit protein eL21, conserved site |
| Family | IPR001147 | Large ribosomal subunit protein eL21 |
| Homologous_superfamily | IPR008991 | Translation protein SH3-like domain superfamily |
| Homologous_superfamily | IPR036948 | Large ribosomal subunit protein eL21 superfamily |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Large ribosomal subunit protein eL21 | Large ribosomal subunit protein eL21, conserved site | Large ribosomal subunit protein eL21 superfamily | Translation protein SH3-like domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q6IQQ0 | InterPro PDB | 160 |
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- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-202A8 | ZFIN Curated Data | |
| Encodes | EST | fb13h07 | ||
| Encodes | EST | fc74e02 | ||
| Encodes | EST | IMAGE:6906305 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:86669 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001002155 (1) | 595 nt | ||
| Genomic | GenBank:AL929009 (1) | 208279 nt | ||
| Polypeptide | UniProtKB:Q6IQQ0 (1) | 160 aa |
- Rojo-Bartolomé, I., Santana de Souza, J.E., Diaz de Cerio, O., Cancio, I. (2020) Duplication and subfunctionalisation of the general transcription factor IIIA (gtf3a) gene in teleost genomes, with ovarian specific transcription of gtf3ab. PLoS One. 15:e0227690
- Ayobahan, S.U., Eilebrecht, E., Kotthoff, M., Baumann, L., Eilebrecht, S., Teigeler, M., Hollert, H., Kalkhof, S., Schäfers, C. (2019) A combined FSTRA-shotgun proteomics approach to identify molecular changes in zebrafish upon chemical exposure. Scientific Reports. 9:6599
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Provost, E., Weier, C.A., and Leach, S.D. (2013) Multiple ribosomal proteins are expressed at high levels in developing zebrafish endoderm and are required for normal exocrine pancreas development. Zebrafish. 10(2):161-169
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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