ZFIN is now using GRCz12tu for Genomic Data
Gene
fgfbp2a
- ID
- ZDB-GENE-030131-8319
- Name
- fibroblast growth factor binding protein 2a
- Symbol
- fgfbp2a Nomenclature History
- Previous Names
-
- fgfbp2
- fb08g06
- wu:fb08g06
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable growth factor binding activity. Predicted to be involved in cell-cell signaling. Predicted to be located in extracellular region. Is expressed in head; liver; and pharyngeal arch 2. Orthologous to human FGFBP2 (fibroblast growth factor binding protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR010510 | FGF binding 1 |
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Domain Details Per Protein
| Protein | Additional Resources | Length | FGF binding 1 |
|---|---|---|---|
| UniProtKB:F1R8L1 | InterPro | 215 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fgfbp2a-201
(1)
|
Ensembl | 1,497 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-13A3 | ZFIN Curated Data | |
| Contains | SNP | rs3728667 | ZFIN Curated Data | |
| Contains | SNP | rs3728668 | ZFIN Curated Data | |
| Contains | SNP | rs3728669 | ZFIN Curated Data | |
| Encodes | EST | fb08g06 |
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| Type | Accession # | Genome Assembly | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001386311 (1) | 1527 nt | ||
| Genomic | GenBank:BX004823 (2) | 197683 nt | ||
| Polypeptide | UniProtKB:F1R8L1 (1) | 215 aa |
- Madera, D., Alonso-Gómez, A., Delgado, M.J., Valenciano, A.I., Alonso-Gómez, Á.L. (2023) Gene Characterization of Nocturnin Paralogues in Goldfish: Full Coding Sequences, Structure, Phylogeny and Tissue Expression. International Journal of Molecular Sciences. 25(1):
- Jiang, M., Xiao, Y., E, W., Ma, L., Wang, J., Chen, H., Gao, C., Liao, Y., Guo, Q., Peng, J., Han, X., Guo, G. (2021) Characterization of the Zebrafish Cell Landscape at Single-Cell Resolution. Frontiers in cell and developmental biology. 9:743421
- Li, Y., Sun, S., Ding, Z., Yang, C., Zhang, G., Jiang, Q., Zou, Y. (2018) Temporal and spatial expression of fgfbp genes in zebrafish. Gene. 659:128-136
- Askary, A., Xu, P., Barske, L., Bay, M., Bump, P., Balczerski, B., Bonaguidi, M.A., Crump, J.G. (2017) Genome-wide analysis of facial skeletal regionalization in zebrafish. Development (Cambridge, England). 144(16):2994-3005
- Rabinowitz, J.S., Robitaille, A.M., Wang, Y., Ray, C.A., Thummel, R., Gu, H., Djukovic, D., Raftery, D., Berndt, J.D., Moon, R.T. (2017) Transcriptomic, proteomic, and metabolomic landscape of positional memory in the caudal fin of zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 114(5):E717-E726
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Crespo, D., Assis, L.H., Furmanek, T., Bogerd, J., Schulz, R.W. (2016) Expression profiling identifies Sertoli and Leydig cell genes as Fsh targets in adult zebrafish testis. Molecular and Cellular Endocrinology. 437:237-251
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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