Gene

prg4a

ID
ZDB-GENE-030131-8295
Name
proteoglycan 4a
Symbol
prg4a Nomenclature History
Previous Names
  • fb08a02
  • wu:fb08a02
  • wu:fk21a06
  • zgc:56698
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable polysaccharide binding activity and scavenger receptor activity. Predicted to act upstream of or within immune response. Predicted to be located in extracellular region. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in caudal fin. Human ortholog(s) of this gene implicated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome and pericarditis. Orthologous to human PRG4 (proteoglycan 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Nolte et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prg4a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
camptodactyly-arthropathy-coxa vara-pericarditis syndrome Alliance Camptodactyly-arthropathy-coxa vara-pericarditis syndrome 208250
Associated With prg4a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001212 Somatomedin B domain
Homologous_superfamily IPR036024 Somatomedin B-like domain superfamily
Homologous_superfamily IPR036375 Hemopexin-like domain superfamily
Repeat IPR018487 Hemopexin-like repeats
Domain Details Per Protein
Protein Length Hemopexin-like domain superfamily Hemopexin-like repeats Somatomedin B domain Somatomedin B-like domain superfamily
UniProtKB:F1R2Z8 298
UniProtKB:B8JMI5 486
UniProtKB:Q7ZW66 486
UniProtKB:B8JMI4 129
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations