Gene
ttbk2b
- ID
- ZDB-GENE-030131-8246
- Name
- tau tubulin kinase 2b
- Symbol
- ttbk2b Nomenclature History
- Previous Names
-
- fj62e10
- sb:eu1102
- si:dkey-12h9.11
- si:dkey-12h9.14
- wu:fj62e10
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Predicted to be involved in cilium assembly and peptidyl-serine phosphorylation. Predicted to localize to several cellular components, including ciliary basal body; ciliary transition zone; and nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Orthologous to human TTBK2 (tau tubulin kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1102 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spinocerebellar ataxia type 11 | Alliance | Spinocerebellar ataxia 11 | 604432 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Tau-tubulin kinase homolog Asator-like, catalytic domain |
|---|---|---|---|---|---|
|
UniProtKB:F1RC23
|
928 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
ttbk2b-201
(1)
|
Havana | 5277 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance