Gene

loxl3b

ID
ZDB-GENE-030131-8210
Name
lysyl oxidase-like 3b
Symbol
loxl3b Nomenclature History
Previous Names
  • fj60c12
  • im:7157119
  • wu:fj60c12
  • zgc:162959
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to enable fibronectin binding activity and protein-lysine 6-oxidase activity. Acts upstream of or within embryonic viscerocranium morphogenesis. Predicted to be located in cytoplasm and nucleus. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, including axis; head; mesoderm; pectoral fin cartilage; and yolk syncytial layer. Human ortholog(s) of this gene implicated in myopia. Orthologous to human LOXL3 (lysyl oxidase like 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
23 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With loxl3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Myopia 28, autosomal recessive 619781
Associated With loxl3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019828 Lysyl oxidase, conserved site
Domain IPR001190 SRCR domain
Domain IPR017448 SRCR-like domain
Family IPR001695 Lysyl oxidase
Homologous_superfamily IPR036772 SRCR-like domain superfamily
Domain Details Per Protein
Protein Length Lysyl oxidase Lysyl oxidase, conserved site SRCR domain SRCR-like domain SRCR-like domain superfamily
UniProtKB:B8A5R6
UniProtKB:B8A5R8
UniProtKB:A0A5H1ZRH8 268
UniProtKB:B8A4W9 807
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations