Gene
grm2a
- ID
- ZDB-GENE-030131-8097
- Name
- glutamate receptor, metabotropic 2a
- Symbol
- grm2a Nomenclature History
- Previous Names
-
- mglur2a (1)
- wu:fj52c07
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable group II metabotropic glutamate receptor activity. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in dendrite; membrane; and synapse. Predicted to be active in plasma membrane. Is expressed in brain; retinal neural layer; and trigeminal ganglion. Orthologous to human GRM2 (glutamate metabotropic receptor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Haug et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017979 | GPCR, family 3, conserved site |
| Domain | IPR001828 | Receptor, ligand binding region |
| Domain | IPR011500 | GPCR, family 3, nine cysteines domain |
| Domain | IPR017978 | GPCR family 3, C-terminal |
| Family | IPR000162 | GPCR, family 3, metabotropic glutamate receptor |
| Family | IPR000337 | GPCR, family 3 |
| Family | IPR001458 | GPCR, family 3, metabotropic glutamate receptor 2 |
| Family | IPR050726 | Metabotropic Glutamate Receptor |
| Homologous_superfamily | IPR028082 | Periplasmic binding protein-like I |
| Homologous_superfamily | IPR038550 | GPCR, family 3, nine cysteines domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, family 3 | GPCR, family 3, conserved site | GPCR family 3, C-terminal | GPCR, family 3, metabotropic glutamate receptor | GPCR, family 3, metabotropic glutamate receptor 2 | GPCR, family 3, nine cysteines domain | GPCR, family 3, nine cysteines domain superfamily | Metabotropic Glutamate Receptor | Periplasmic binding protein-like I | Receptor, ligand binding region |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2BDP3 | InterPro | 894 | ||||||||||
| UniProtKB:U3N5X6 | InterPro | 887 |
Interactions and Pathways
No data available
Plasmids
No data available