Gene
plin3
- ID
- ZDB-GENE-030131-7218
- Name
- perilipin 3
- Symbol
- plin3 Nomenclature History
- Previous Names
-
- fl05f04
- si:rp71-61h23.4
- wu:fl05f04 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Located in cytoplasm. Is expressed in intestine. Orthologous to several human genes including PLIN3 (perilipin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Wilson et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| c875Tg | Transgenic insertion | Unknown | Unknown | DNA and TALEN |
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Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR004279 | Perilipin |
1 - 1 of 1
Domain Details Per Protein
| Protein | Additional Resources | Length | Perilipin |
|---|---|---|---|
| UniProtKB:F1QGJ3 | InterPro | 416 |
1 - 1 of 1
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zgc:77486-201
(1)
|
Ensembl | 1,696 nt | ||
| mRNA |
zgc:77486-202
(1)
|
Ensembl | 4,081 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
| Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
|---|---|---|---|---|---|
| Tg(fabp2:plin3-EGFP) |
|
| 1 | Wilson et al., 2021 | |
| Tg(hsp70l:plin3-EGFP) |
|
| 1 | Wilson et al., 2021 |
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| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-222F22 | ZFIN Curated Data | |
| Encodes | EST | fl05f04 |
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- Grepper, D., Tabasso, C., Aguettaz, A., Martinotti, A., Ebrahimi, A., Lagarrigue, S., Amati, F. (2023) Methodological advancements in organ-specific ectopic lipid quantitative characterization: Effects of high fat diet on muscle and liver intracellular lipids. Molecular metabolism. 68:101669
- Le Mentec, H., Monniez, E., Legrand, A., Monvoisin, C., Lagadic-Gossmann, D., Podechard, N. (2023) A New In Vivo Zebrafish Bioassay Evaluating Liver Steatosis Identifies DDE as a Steatogenic Endocrine Disruptor, Partly through SCD1 Regulation. International Journal of Molecular Sciences. 24(4):
- Sun, Y., Heng, J., Liu, F., Zhang, S., Liu, P. (2023) Isolation and proteomic study of fish liver lipid droplets. Biophysics reports. 9:120133120-133
- Wilson, M.H., Ekker, S.C., Farber, S.A. (2021) Imaging cytoplasmic lipid droplets in vivo with fluorescent perilipin 2 and perilipin 3 knock-in zebrafish. eLIFE. 10
- Sæle, Ø., Rød, K.E.L., Quinlivan, V.H., Li, S., Farber, S.A. (2018) A novel system to quantify intestinal lipid digestion and transport. Biochimica et biophysica acta. 1863(9):948-957
- Granneman, J.G., Kimler, V.A., Zhang, H., Ye, X., Luo, X., Postlethwait, J.H., Thummel, R. (2017) Lipid droplet biology and evolution illuminated by the characterization of a novel Perilipin in teleost fish. eLIFE. 6
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