Gene
akap1b
- ID
- ZDB-GENE-030131-6844
- Name
- A kinase (PRKA) anchor protein 1b
- Symbol
- akap1b Nomenclature History
- Previous Names
-
- akap1
- fa08b04
- wu:fa08b04 (1)
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable protein kinase A regulatory subunit binding activity. Predicted to act upstream of or within phosphorylation. Predicted to be active in membrane and mitochondrion. Is expressed in several structures, including alar plate midbrain region; digestive system; midbrain; musculature system; and segmental plate. Orthologous to human AKAP1 (A-kinase anchoring protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb434 (17 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
sa32042 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | A-kinase anchor protein 1, Tudor domain | A-kinase anchor protein 1, type I K homology domain | K Homology domain | K Homology domain, type 1 | K Homology domain, type 1 superfamily | SNase-like, OB-fold superfamily | Tudor domain | Tudor domain-containing |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:F1RBY1 | InterPro | 837 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
akap1b-201
(1)
|
Ensembl | 6,341 nt | ||
mRNA |
akap1b-204
(1)
|
Ensembl | 3,083 nt | ||
ncRNA |
akap1b-003
(1)
|
Ensembl | 823 nt | ||
ncRNA |
akap1b-004
(1)
|
Ensembl | 880 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-209M20 | ZFIN Curated Data | |
Contains | SNP | rs3728735 | ZFIN Curated Data | |
Encodes | EST | cb434 | Thisse et al., 2001 | |
Encodes | EST | fa08b04 | ||
Has Artifact | cDNA | MGC:162884 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001098179 (1) | 3083 nt | ||
Genomic | GenBank:BX000438 (1) | 195087 nt | ||
Polypeptide | UniProtKB:F1RBY1 (1) | 837 aa |
- Zhang, J., Li, P., Sun, L., Jiang, N., Guo, W., Wang, J., Gao, F., Li, J., Li, H., Zhang, J., Mu, H., Hu, Y., Cui, X. (2023) Knockout of miR-184 in zebrafish leads to ocular abnormalities by elevating p21 levels. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 37:e22927e22927
- Burkhalter, M.D., Sridhar, A., Sampaio, P., Jacinto, R., Burczyk, M.S., Donow, C., Angenendt, M., Investigators, C.N.F.C.H.D., Hempel, M., Walther, P., Pennekamp, P., Omran, H., Lopes, S.S., Ware, S.M., Philipp, M. (2019) Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis. The Journal of Clinical Investigation. 130:2841-2855
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Zhou, S., Zhao, H., Thongda, W., Zhang, D., Su, B., Yu, D., Peatman, E., Li, C. (2016) Galectins in channel catfish, Ictalurus punctatus: Characterization and expression profiling in mucosal tissues. Fish & shellfish immunology. 49:324-35
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Huang, H.T., Kathrein, K.L., Barton, A., Gitlin, Z., Huang, Y.H., Ward, T.P., Hofmann, O., Dibiase, A., Song, A., Tyekucheva, S., Hide, W., Zhou, Y., and Zon, L.I. (2013) A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nature cell biology. 15(12):1516-1525
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